Modulation of portal vein hemodynamics by selective splenectomy to prevent small-for-size syndrome in living donor liver transplantation
10.3760/cma.j.issn.1007-8118.2011.11.012
- VernacularTitle:选择性脾切除调整门静脉血流预防活体肝移植小肝综合征
- Author:
Honghai WANG
;
Wentao JIANG
;
Qingjun GUO
;
Lin WEI
;
Zhijun ZHU
- Publication Type:Journal Article
- Keywords:
Living donor liver transplantation;
Small-for-size syndrome;
Portal vein flow;
Splenectomy
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(11):909-911
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effects of selective splenectomy on modulation of portal vein flow and prevention of small-for-size syndrome (SFSS) in living donor liver transplantation.MethodsTwenty six recipients who received LDLT from September 2007 to March 2008 were reviewed.The data of the portal vein flow of these recipients were collected during the operation.Simultaneous splenectomy was performed in patients with portal blood flow ＞250 ml/(min · 100g).No splenectomy was performed when the portal blood flow was less than 250 ml/(min · 100g).The effect of selective splenectomy on modulation of portal vein flow and whether splenectomy prevented the occurrence of SFSS were analyzed.ResultsThe portal vein flow decreased significantly after splenectomy in 8 patients who received splenectomy (P＜0.01),No SFSS occurred in the patients with or without splenectomy.Actual graft-to-recipient weight ratio (GRWR) of patients with splenectomy was significantly smaller than those with no splenectomy (P=0.044).The portal vein flow of patients with splenectomy was much higher than those with no splenectomy (P＜0.01).ConclusionAccording to the portal blood flow,selective splenectomy in LDLT decreased the portal vein flow and prevented the incidence of SFSS.
