Treatment of chronic obstructive pulmonary disease with salmeterol/fluticasone propionate and community intervention
10.3760/cma.j.issn.1671-7368.2011.12.006
- VernacularTitle:沙美特罗替卡松粉吸入剂联合社区干预治疗慢性阻塞性肺疾病
- Author:
Bing ZHANG
;
Yulong ZHENG
;
Suhua YANG
;
Liyang ZHOU
;
Shu LIU
;
Yuanqiang HE
- Publication Type:Journal Article
- Keywords:
Pulmonary disease;
chronic obstructive;
Prognosis;
Community intervention
- From:
Chinese Journal of General Practitioners
2011;10(12):864-867
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of salmeterol/fluticasone (seretide) combined with community intervention on lung function and quality of life of chronic obstruetive pulmonary disease (COPD) patients in the stable period.Methods 96 cases with COPD in the stable period were divided into two groups randomly:Group A was treated only by seretide for six months,group B was treated by seretide combined with community intervention (health education,psychological intervention,exercise training,and nutritional guidance).6 months later,the lung function was determined and the quality of life was assessed by SGRQ.Results The lung function and the score of the quality of life in two groups after treatment [Group A:(1.78 ±0.16)L,(65 ±9)％ and 40 ± 18,36 ± 16,125 ±40;group B:(2.05 ±0.28)L,(73 ±9)％ and 21 ± 10,20 ± 11,58 ± 28,respectively] were improved than those before treatment [Group A:(1.59 ±0.15),(58 ±7) and 63 ±22,50 ±24,167 ±68;group B:(1.61 ±0.14)L,(58 ± 8)％ and 62 ±22,48 ± 22,163 ± 67,respectively] (P ＜ 0.05 );The lung function and the score of the quality of life in B group were improved than those in A group after treatment ( P ＜ 0.05 ).Conclusions Using community intervention combined with seretide in treatment of COPD patients has better effect than the single use of seretide therapy,it improves lung function and quality of life.It is a safe treatment method and worthy to spread widely.
