Influencing factors in quality of life of patients with hepatolenticular degeneration
10.3760/cma.j.issn.1674-6554.2011.11.020
- VernacularTitle:肝豆状核变性患者的生活质量及影响因素
- Author:
Xinfeng MA
;
Gongqiang WANG
;
Jiyuan HU
;
Bo LI
;
Yongzhu HAN
- Publication Type:Journal Article
- Keywords:
Hepatolenticular degeneration;
Wilson's disease;
Quality of life;
Influencing factors
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2011;20(11):1022-1024
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the quality of life of patients with hepatolenticular degeneration (HLD)and analyze the influencing factors.Methods287 patients with HLD and 51 health people were investigated by World Health Organization quality of life assessment instrument brief version (WHOQOL-BREF),Symptom Checklist 90 (SCL-90),Life Satisfaction Index A (LSIA) and variance analysis,t-test and multiple linear regression analysis were analyzed the influencing factors.Results①Scores of WHOQOL-BREF:physical domain(54.64 ± 17.11 ),psychological domain ( 52.09 ± 15.83 ) in patients with HLD were lower than those in the health people (67.30 ± 12.66,58.90 ± 12.75 ) with statistically significant difference (P ＜ 0.01 ) ; social domain ( 51.35± 17.18),the domain of environment(53.54 ± 16.67) in patients with HLD were lower than those in the health people (57.53 ± 14.99,58.42 ± 10.55 ) with statistically significant difference (P ＜ 0.05 ).②The quality of life of the patients with HLD was influenced by LSIA,total score of SCL-90,the attitude toward the doctors,economic status,the attitude toward the disease,residence with statistically significant difference (P ＜ 0.0l ).ConclusionThe quality of life in patients with HLD is lower than that in health people and much factors influence it,so it is necessary to take multi-facet interventions to improve their quality of life.
