Oral mucosal grafts urethroplasty for the treatment of anterior urethral strictures: a ten-year clinicalexperience
10.3760/cma.j.issn.1000-6702.2011.11.003
- VernacularTitle:口腔内黏膜尿道成形治疗前尿道狭窄10年经验总结
- Author:
Lujie SONG
;
Yuemin XU
;
Qiang FU
;
Yinglong SA
;
Jiong ZHANG
;
Hong XIE
;
Chongrui JIN
;
Jiemin SI
;
Xiaoyong HU
;
Chao LI
- Publication Type:Journal Article
- Keywords:
Mouth mucosa;
Urethral stricture;
Buccal mucosa;
Lingual mucosa;
Urethroplasty
- From:
Chinese Journal of Urology
2011;32(11):728-731
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the efficacy of using oral mucosal grafts (buccal mucosa and lingual mucosa) for urethroplasty in the treatment of anterior urethral strictures. Methods Between Jan 2001 and Dec 2010,255 patients with urethral strictures (length ranging from 3 cm to 18 cm,mean 6 cm)underwent one-stage onlay oral mucosal grafts urethroplasty.Two different techniques were used for urethral reconstruction.The first technique involved tubularized dorsal lingual mucosa graft (LMG) augmentation of urethral plate ; the second technique used dorsal patch graft urethroplasty.Of the 255 patients,49 patients with long-segment urethral strictures ( ≥ 8 cm) underwent dual buccal mucosal graft ( BMG),dual LMG,combined LMG and BMG or long-strip LMG urethroplasty. ResultsThe patients were followed up for 8 -120 months postoperatively ( mean 37 months).Of the 255 cases,230 cases voided well and the urinary peak flows ranged from 16 to 51 ml/s (mean 26 ml/s).The overall success rate was 90.2％.Seventeen cases developed a recurrence of urethral stricture.Among these patients,15 underwent BMG urethroplasty again and 2 underwent direct vision internal urethrotomy,after which the patients voided well.Eight cases presented with urethrocutaneous fistula,these patients underwent a second operation,after which,the urethrocutaneous fistulas were cured. Conclusions The buccal mucosa and lingual mucosa are excellent sources of graft materials for the repair of anterior urethral strictures.Combined two oral mucosal grafts substitution urethroplasty is an effective technique for the treatment of long-segment urethral strictures.
