The relationship between operation scores and the expression of caveolin-1 protein in the cortex of mice
10.3760/cma.j.issn.1674-6554.2011.10.003
- VernacularTitle:小鼠皮层eaveolin-1蛋白表达与作业成绩的相关性
- Author:
Yongliang LIAN
;
Ping ZOU
;
Yini MA
;
Xiuwen WANG
;
Jiajia WANG
;
Dannv HAN
;
Xiaofeng LIANG
;
Wei ZOU
- Publication Type:Journal Article
- Keywords:
Caveolin-1;
Operation scores;
Mice;
Cortex
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2011;20(10):872-874
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between operation scores and the expression of caveolin-1 ( Cav-1 ) protein in the cortex of mice.Methods Male Kunming mice were used and divided into two groups (excellent group and bad group) according to the training scores after 4 days' Y-maze learning training.The expression of cav-1 protein in cortex and hippocampus of the mice with different scores were measured through Western blot technology.Results Cav-1 protein expression of excellent group( Cav-1/β-actin was 5.71 + 1.11 ) in the cortex was significantly higher than that of the bad group ( Cav-1/β-actin was 1.69 + 0.20) (P ＜ 0.01 ).While there was no significant difference in the two groups in the expression of Cav-1 protein in hippocampus(P ＞ 0.05 ).Conclusion The operation scores have distinct correlation with the expression of Cav-1 protein in the cortex of mice.
