Influential factors of brachial-ankle artery pulse wave velocity in healthy subjects

VernacularTitle:肱踝动脉脉搏波传导速度在健康体检中的应用及相关因素分析
Author: Jie SUN ; Zhenjie WANG ; Wei YANG ; Shengsheng WANG ; Xiaorong GAI
Publication Type:Journal Article
Keywords: Arteries; Pulse wave velocity; Regression analysis
From: Chinese Journal of General Practitioners 2011;10(11):801-803
CountryChina
Language:Chinese
Abstract: Objective To investigate the influential factors of brachial-ankle artery pulse wave velocity (baPWV) in healthy individuals.Methods Total 716 healthy subjects including 503 males and 213 females,who underwent health check up in 2010,were enrolled in the study Bilateral baPWV was examined in all subjects and multiple factor linear regression was applied to evaluate the correlations of baPWV with sex,age,body mass index,arterial blood pressure,ankle-brachial index and biochemical variables.Results The mean baPWV of 716 healthy subjecs was ( 1224 ± 162) cm/s,and there was significant difference between men and women [ ( 1257 ± 159) cm/s vs.( 1144 ± 143) cm/s].There was a significant linear correlation of baPWV with sex,age,mean arterial blood pressure and plasma homocysteine concentration ; and the linear regression equation was:mean PWV =6.635 × age + 7.285 × mean arterial blood pressure + 2.682 × homocysteine concentration - 64.334 × sex + 347.500 ( sex:man =0,woman =1 ).Conclusion Age,sex,mean arterial blood pressure and plasma homocysteine concentration are independent influential factors of baPWV.