Experimental study of the change of early regional myocardial function with diabetic using omni-directional Mmode echocardiography

VernacularTitle:全方向M型超声心动图对糖尿病心肌局部功能早期改变的实验研究
Author: Wei GUO ; Zhensheng YE ; Ying DAI ; Bin CHEN
Publication Type:Journal Article
Keywords: Echocardiography; Diabetes mellitus; Ventricular function,left
From: Chinese Journal of Ultrasonography 2011;20(10):883-886
CountryChina
Language:Chinese
Abstract: ObjectiveTo evaluate the role of detecting early change of left ventricular regional myocardial function in the rabbit with type Ⅰ diabetes using omni-directional M-mode echocardiography (OME).MethodsEighty New Zealand rabbits were selected in this study..40 health rabbits were included in the control group,the other 40 with type Ⅰ diabetes were included in the experiment group.The OME was used to measure the peak time of myocardial motion during systole (Ts) and diastole (Td),myocardial velocity gradient during systole (MVGs) and diastole (MVGd) on the left ventricular short axis.These parameters were measured during the first,second,fourth,sixth and eighth week.ResultsOME was able to detect significant changes of Td during the second week,Ts and MVGd during the fourth week,and MVGs during sixth week after modeling ( P ＜0.05 ).ConclusionsOME is an important method to detect early changes of regional myocardial function in the patients with diabetes.