Progress in the protective action of liraglutide on the islet β cells
10.3760/cma.j.issn.1000-6699.2011.10.025
- VernacularTitle:利拉鲁肽对胰岛β细胞保护作用的研究进展
- Author:
Xiaohui GUO
- Publication Type:Journal Article
- Keywords:
Glucagon like peptide-1;
Liraglutide;
Diabetic mellitus,type 2;
Islet β cell
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(10):877-880
- CountryChina
- Language:Chinese
-
Abstract:
The failure of islet β cell is the core pathogenic mechanism of diabetes,which is also the key target for type 2 diabetic mellitus treatment.A large amount of basic and clinical researches have been confirmed that glucagon like peptide-1 and its analogue liraglutide have abilities to significantly improve islet β cell function besides the glucose-dependent lowering hyperglycemia effects.Furthermore,liraglutide is approved to improve β cell function,thus providing a new choice for treatment of type 2 diabetes.
