Analysis on 128 cases of advanced pancreatic cancer treated by high intensity focused ultrasound
10.3760/cma.j.issn.1007-8118.2011.10.028
- VernacularTitle:高强度聚焦超声治疗晚期胰腺癌128例分析
- Author:
Kun WANG
;
Zhiqiang MENG
;
Zhen CHEN
;
Luming LIU
;
Junhua LIN
;
Zhenhua ZHOU
;
Hao CHEN
;
Peng WANG
;
Lianyu CHEN
- Publication Type:Journal Article
- Keywords:
Pancreatic carcinoma;
Cancer pain;
High intensity focused ultrasound
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(10):871-872
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the analgesic efficacy and effect of high intensity focused ultrasound (HIFU) in the treatment of advanced pancreatic cancer.Methods128 patients with pancreatic cancer ( Ⅲ stage 41 case,Ⅳ stage 87 case) were treated by HIFU.According to some parameters,such as the clinical symptoms,imaging examinations and survival analysis to assess the efficacy of HIFU treatment.Results22.9% patients’ serum Ca19-9 decreased.The cancer pain was relieved in 72.5% patients.Coagulated-necrosis by CT/MRI examination was observed.PR,SD and PD of all were 11.7%,70.3% and 18.0% respectively.1-year survival rate was 16.7% for all patients,and median survival time was 7.0 months.1-year survival rate and median survival time for Ⅲ stage group were 28.5% and 9.0 months,that of 10.8% and 6.0 months for Ⅳ stage group respectively.ConclusionHIFU may benefit to advanced pancreatic cancer patient by stabilizing tumors,relieving pain and prolonging life expectancy with less side effects.