Analysis of ischemic stroke in the elderly from single center based on TOAST
10.3760/cma.j.issn.0254-9026.2011.10.002
- VernacularTitle:采用TOAST分型对高龄缺血性脑卒中患者的单中心资料分析
- Author:
Hongbing CHEN
;
Ying WANG
;
Juanjuan HE
;
Wenjin SHANG
;
Hua HONG
- Publication Type:Journal Article
- Keywords:
Stroke;
Diagnosis,differential
- From:
Chinese Journal of Geriatrics
2011;30(10):800-804
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the differences of clinical features,neuroimaging,angiography and laboratory findings between different stroke subtypes according to TOAST criteria in elderly patients.Methods 91 patients (aged ≥ 80 years) with acute ischemic stroke were retrospectively reviewed in Departement of Neurology from April 2009 to August 2010.Subtypes of ischemic stroke were analyzed according to the classification of TOAST.Risk factors,clinical manifestations,complications,prognosis,neuroimaging,cerebrovascular lesions,and laboratory findings of different TOAST subtypes were compared.Results Large-artery atherosclerosis (LAA) (34/91) was the most common cause of acute ischemic stroke in elderly patients,and most criminal lesions (25/34) located at the intracranial arteries.In the LAA group,patients with intracranial (25/34) or extracranial (12/34) occlusive diseases were more than those in other groups.Patients with cardioembolism (CE) had lower lipid levels.In the CE group,patients with poor shortterm prognosis (7/15) were more than in the LAA or small-artery occlusion (SAO) group,and patients with severe cerebral edema (4/15) were more than those in other groups.In patients of the SAO group,complications occurred infrequently (4/20),and none had poor short-term prognosis.Conclusions There were some differences among different TOAST subtypes in clinical features,neuroimaging,cerebrovascular diseases,and laboratory findings.The clinical significance of our findings needs to be explored further.
