Colorectal carcinoma with schistosomiasis among elderly people in the district of petrochemical industry in Shanghai: Analysis of clinical pathological characteristics and prognosis
10.3760/cma.j.issn.0254-9026.2011.10.012
- VernacularTitle:上海石化地区老年人血吸虫病相关性结直肠癌临床病理特征及预后分析
- Author:
Zebing LIU
;
Li WANG
;
Yu YANG
;
Xuanguang YE
;
Youyuan ZHANG
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasm;
Schistosomiasia,japonica
- From:
Chinese Journal of Geriatrics
2011;30(10):836-838
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of schistosomiasis on malignant bio-behaviors including histological types,differentiation grade,inasie depth,lymphnode metastasis and prognosis of colorectal carcinoma among elderly people in the district of petrochemical industry,Shanghai.Methods A total of 184 cases (aged 60 years and over) with specimens of colorectal cancer were collected from January 2004 to December 2010.These specimens were divided into colorectal carcinoma with schistosomiasis (CRCS) group (102 cases) and simple colorectal carcinoma (CRC) as control group (82 cases).The prognostic data of 40 elderly cases with colorectal carcinoma from January 2004 to December 2006 were simultaneously selected and analysed Results Totally 55.4％ (102/184) cases exhibited coexistent schistosomiasis with colorectal carcinoma.lesion site(x2=16.53),growth pattern(x2 =10.81 ),differentiation degree(x2 =10.46),infiltration degree(x2 =6.71),lymph node metastasis(x2 =3.90),and TNM staging(x2=5.73) in CRCS group were closely related to schistosomiasis compared with CRC group (P＜0.05).Survival curve analysis showed that there was no significant effect of schistosomiasis on the survival time of elderly patients with colorectal carcinoma (x2 =0.14,P＞0.05).Conclusions The coexistent schistosomiasis may be associated with the malignant bio-behaviors of colorectal carcinoma among the elderly,but have no significant influence on the survival time after operation.
