Target volume determination of postoperative 125I seeds interstitial brachytherapy in parotid gland carcinoma
10.3760/cma.j.issn.0254-5098.2011.05.015
- VernacularTitle:腮腺癌术后125I粒子组织间近距离治疗靶区确定方法的探讨
- Author:
Tieli SONG
;
Lei ZHENG
;
Mingwei HUANG
;
Jie ZHANG
;
Hongzhi ZHANG
;
Jianguo ZHANG
- Publication Type:Journal Article
- Keywords:
125 I seeds;
Interstitial brachytherapy;
Target volume;
Parotid region
- From:
Chinese Journal of Radiological Medicine and Protection
2011;31(5):564-566
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the method of target volume determination of postoperative 125I seeds interstitial brachytherapy in parotid gland carcinoma.Methods A total of 31 cases( 14 males and 17 famales) with primary parotid carcinoma who were treated in Peking University Hospital of Stomatology from Oct 2002 to Nov 2006.The patients' average age was 38.2 years.All patients underwent tumor resection and postoperative 125I seeds interstitial brachytherapy with 60 Gy matched peripheral dose.The spiral CT was performed for treatment plan and quality verification before and after the brachytherapy.The bone and muscle landmarks surrounding parotid were selected as reference for target volume determination.D90 of target volume and dose of organs at risk were calculated,while the target volume and D90 of target volume of verification were compared with that of treatment plan through quality verification.Results The target volume or D90 of target volume before and after treatment was not statistically different.D90 of target volume was more than 60 Gy.During 3 -7 years of follow-up,all patients had no recurrence.ConclusionsAccording to the follow-up results,the method used for target volume determination in this paper might be satisfied.