Detection of oqxA gene from multidrug resistant Klebsiella pneumoniae
10.3760/cma.j.issn.1674-2397.2011.05.009
- VernacularTitle:国内首次从多重耐药肺炎克雷伯菌中检出oqxA基因
- Author:
Jie ZHU
;
Feng ZHANG
;
Yuhong PAN
;
Xuan HUANG
;
Huali CHENG
;
Guozhong Lü
;
Zuhuang MI
- Publication Type:Journal Article
- Keywords:
Klebsiella pneumoniae;
Efflux pump genes;
Antibacterial agents
- From:
Chinese Journal of Clinical Infectious Diseases
2011;04(5):284-287
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of multidrug resistant genes in Klebsiella pncumoniae.MethodsTwenty strains of multidrug resistant Klebsiella pneumoniae were isolated from burn patients.Susceptibility of these strains to 14 antibiotics was detected by KB method.PCR was used to detect oqxA,smrKpn,qacE,tehA,mdfA and qacEΔl-sul1 genes.ResultsThe antibiotic sensitivity rates of 20 multidrug resistant Klebsiella pneumoniae isolates to antibiotics tested were ＜ 30％ except that to imipenam.The positive rates of efflux pump genes mdfA,qacEΔl-sull and oqxA were 65％,100％ and 100％,respectively; while those ofsmrKpn,qacE and tehA were 0％,0％ and 15％.ConclusionoqxA gene has been detected in multidrug resistant Klebsiella pneumoniae from burn patients with high positive rate.
