The study of laparoscopic-guided radiofrequency ablation of prostate cancer
10.3760/cma.j.issn.1673-4904.2011.29.005
- VernacularTitle:腹腔镜前列腺癌射频消融术的应用研究
- Author:
Bin GUO
;
Wenqi WU
;
Xiaogang LU
;
Dongliang ZHONG
;
Chichang SHAN
- Publication Type:Journal Article
- Keywords:
Laparoscopes;
Catheter ablation;
Prostatic neoplasms
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(29):14-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the feasibility and efficiency of laparoscopic-guided radiofrequency ablation on advanced prostate cancer.Methods From March 2003 to December 2008,a total of 6 previous prostate cancer patients who had been diagnosed with pathological results were treated by laparoscopic-guided radiofrequency ablation.All patients underwent pre-and post-operative IPSS,serum PSA,MRI and normal blood biochemistry examination.The treatment outcome,surgery-related complications were also recorded.Results All operations were successfully completed,no serious intra-and post-operative complications happened.Although there was no significant difference of IPSS between pre-operative [ ( 19.05 + 4.28 ) scores ] and 1 month after operation [ ( 19.87 + 5.72) scores ],but there were significantly decreased in 3 months [ (9.45 ± 2.03 ) scores ] and 6 months [ (6.18 + 1.79) scores ] after operation (P <0.05).Also being followed up to 6 months after operation,the serum PSA was significantly decreased compared with the pre-operative value [from(24.80 ± 14.56) μ g/L reduced to( 13.79 ± 7.76) μ g/L](P<0.05).Conclusion Laparoscopic-guided radiofrequency ablation on advanced prostate cancer is safe and feasible,and can be used as an effective treatment in selective cases.