Immunoregulation of galectins in tumor microenvironment
10.3760/cma.j.issn.1673-422X.2011.11.008
- VernacularTitle:半乳糖凝集素在肿瘤微环境中的免疫调节作用
- Author:
Zhaohui CHU
;
Xiaohua LIANG
- Publication Type:Journal Article
- Keywords:
Galectins;
Neoplasms;
Immunity,cellular
- From:
Journal of International Oncology
2011;38(11):826-829
- CountryChina
- Language:Chinese
-
Abstract:
Galectins can recognize and specifically bind to β-galactosidase,and regulate the transformation and survival of tumor cells,and promote the migration and metastasis of tumor cells,etc.Galectins correlate with tumor diagnosis,progression and prognosis.Galectias also can serve as immunoregulatory molecules to regulate the survival,activation,proliferation and differentiation of immune cells,and are components of tumor immune microenvironment.
