Epithelial-mesenchymal transition and cancer stem cells
10.3760/cma.j.issn.1673-422X.2011.11.003
- VernacularTitle:上皮间质转化与肿瘤干细胞
- Author:
Yan GAO
;
Xiumei MA
- Publication Type:Journal Article
- Keywords:
Neoplastic stem cells;
Therapy;
Epithelial-mesenchymal transitions
- From:
Journal of International Oncology
2011;38(11):809-813
- CountryChina
- Language:Chinese
-
Abstract:
Epithelial-mesenchymal transition (EMT) is the basis of biological process of embryonic development,and is also closely related with tumor cell in situ invasion and distant metastasis.Recent studies find that EMT and cancer stem cells (CSCs) have a close relationship.CSCs have a strong ability to selfrenewal,tumorigenicity and cell differentiation potential.Identifing the markers,in-depth study of CSCs resistance,may provide a new path for cancer treatment.