Thrombospondin-1 in cancer
10.3760/cma.j.issn.1673-422X.2011.11.007
- VernacularTitle:凝血酶敏感蛋白-1在肿瘤中的研究进展
- Author:
Peilei ZHAO
;
Ping GUO
- Publication Type:Journal Article
- Keywords:
Thrombospondin 1;
Angiogenesis inhibitors;
Apoptosis;
Three thrombospondin-1 type 1 repeats
- From:
Journal of International Oncology
2011;38(11):823-826
- CountryChina
- Language:Chinese
-
Abstract:
Thrombospondin-1 expresses in a variety of tumors and induces endothelial cell apoptosis,thus inhibits tumor angiogenesis and prevents tumor growth.It function domain ( Type I sequence):3TSR,retaines the function of inhibit angiogenesis,has the certain practical significance in clinical cancer treatment.
