Progress on study of predicting radiosensitivity of esophageal carcinoma
10.3760/cma.j.issn.1673-422X.2011.10.019
- VernacularTitle:食管癌放射敏感性的预测
- Author:
Bo CHEN
;
Liliang YIN
;
Lingli FAN
;
Tao LI
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Radiation tolerance;
Genes,p53;
Receptor,epidermal growth factor
- From:
Journal of International Oncology
2011;38(10):777-780
- CountryChina
- Language:Chinese
-
Abstract:
The radiosensitivity of esophageal carcinoma is one of the bases for making dividualized treatment program.Predition of radiosensitivity before radiotherapy has become a hot spot of the current study.It has been demonstrated that radiosensitivity of esophageal carcinoma is correlated to p53 portein,bcl-2portein,human epidermal growth factor receptors (hEGFR),vascular endothelial growth factor (VEGF),hypoxia-inducible-factor-1 (HIF-1),cyclooxygenase-2(COX-2) and so on.Detection of these markers may be helpful for predicting the radiosensitivity of esophageal carcinonla and making optimal treatment program.In addition,radiosensitivity of tumor can be predicted according to radiation-induced esophagitis grade and endiscopic uhrasonography(EUS).
