MicroRNA in cervical cancer and precancerous lesion
10.3760/cma.j.issn.1673-422X.2011.10.022
- VernacularTitle:微小RNA与宫颈癌及癌前病变的关系
- Author:
Xiaoxia HU
;
Li LI
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Uterine cervical neoplasms;
Precancerous conditions
- From:
Journal of International Oncology
2011;38(10):787-790
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are a class of small,non-coding,single-stand RNA molecules which are composed of 21-25 ribonucleotides.They regulate gene expression at post-transcription and participate in many important biological processes including cell growth,apoptosis,viral infection and cancer development.At present,the studies on miRNAs in cervical lesion include miRNAs expression characteristic of cervical cancer and precancerous lesion,the association with HPV infection and prognosis of cervical lesion,cervical cancer development,diagnosis and therapy.