The Human Microbiome Project: Beginning and Future Status.
10.5145/ACM.2013.16.4.162
- Author:
Patrick R MURRAY
1
Author Information
1. BD Diagnostic Systems, Sparks, Maryland, USA. Patrick_murray@bd.com
- Publication Type:Review
- Keywords:
History;
Human Microbiome;
Metagenome
- From:Annals of Clinical Microbiology
2013;16(4):162-167
- CountryRepublic of Korea
- Language:English
-
Abstract:
In 1884 Robert Koch and Friedrich Loeffler published Koch's Postulates defining our historical understanding of the relationship between an organism and infection: one organism: one disease. In the last decade with research on the microbial community living on and in humans, a new concept of microbial diseases has emerged; that is, alterations of the microbial community can lead to disease including an extension beyond traditional "infectious" diseases to include metabolic disorders such as type 2 diabetes and obesity. As we continue to gain knowledge about the functions of the normal microbiome and the effects of alterations of the microbial population on disease pathogenesis, a new era of diagnostics and therapeutics will evolve.
