Changes and protection of neurovascular unit after cerebral ischemia
10.3760/cma.j.issn.1673-4165.2011.09.011
- VernacularTitle:脑缺血后神经血管单元的变化和保护
- Author:
Hui CHEN
;
Qinghong CUI
;
Yongbo ZHANG
;
Jimei LI
;
Dexin WANG
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Capillaries;
Microcirculation;
Neurons;
Neuroglia;
Blood
- From:
International Journal of Cerebrovascular Diseases
2011;19(9):698-702
- CountryChina
- Language:Chinese
-
Abstract:
The neurovascular unit (NVU) consists of neurons,gllal cells and microvessels,etc.There were complex interactions among the various cellular components,which form as a uniform entirety preferably.Anong the various cellular components of NVU,the signal transduction occurred disorders during cerebral ischemia,resulting in neuronal and extracellular ratrix destruction,and thus occurring cerebral infarction and hemorrhagic transformation.Therefore,the treatment of ischemic sttroke should be based on the protection of the overall function of NVU.This article describes the changes and protection of NVU after cerebral ischemia.