Role of macrophage migration-inhibitory factor in cancer
10.3760/cma.j.issn.1673-422X.2011.10.007
- VernacularTitle:巨噬细胞游走抑制因子在肿瘤中的作用
- Author:
Hongbo ZHANG
;
Jin LIU
- Publication Type:Journal Article
- Keywords:
Macrophage migration-inhibitory factors;
Neoplasms;
apoptosis;
Neoplasm invasiveness
- From:
Journal of International Oncology
2011;38(10):741-744
- CountryChina
- Language:Chinese
-
Abstract:
Macrophage migration-inhibitory factor (MIF) is a cytokine which can promote tumorigenesis.MIF can promote tumorigenesis by directly inducing oncogene transformation,stimulating cell division,as well as indirectly inhibiting tumor apoptosis,promoting its invasiveness and angiogenesis.MIF-targeted biological therapy may become a new therapeutic strategy for malignant tumor.
