Transient receptor potential channels 6 in tumor
10.3760/cma.j.issn.1673-422X.2011.09.005
- VernacularTitle:瞬时受体势6与肿瘤
- Author:
Zhenhua SUN
;
Ping BU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Transient receptor potential channels 6
- From:
Journal of International Oncology
2011;38(9):656-659
- CountryChina
- Language:Chinese
-
Abstract:
Transient receptor potential (TRP) is a kind of novel Ca2+ permeant channel.It is later found that TRP channels are expressed broadly in many organisms,tissues and cell types.It is involved in the regulation of sensory conduction and cell signal transduction.Further studies are required to assess which TRPC6(a member of TRPC subfamily) is associated with the cytosolic Ca2+ levels,development and progression of cancer and tumor cell cycle.TRPC6 may be regarded as new targets for the treatment of cancer.
