Role of n-3 polyunsaturated fatty acid in the combined treatment of breast cancer
10.3760/cma.j.issn.1673-422X.2011.10.013
- VernacularTitle:n-3多不饱和脂肪酸在乳腺癌综合治疗中的作用
- Author:
Feng ZHANG
;
Yiding CHEN
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Metabolism;
Oncogenes
- From:
Journal of International Oncology
2011;38(10):758-761
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is a type of heterogenetic neoplasm.Metabolic dysfunction plays a pivotal role in the pathogenesis and progress of breast cancer.N-3 polyunsaturated fatty acid (PUFA) could change fatty acid metabolism of breast cancer cells and modulate expression of oncogenes and anti-oncogenes through various ways.It may provide therapeutic opportunities in the treatment of chemotherapy,radiotherapy,endocrine therapy and molecule targeted therapy of breast cancer.