Study on Qingre-Huoxue Recipe in improving clinical symptoms of dampness-heat and blood-stasis syndrome of rheumatoid arthritis
10.3760/cma.j.issn.1673-4246.2011.10.003
- VernacularTitle:清热活血方药改善活动期类风湿关节炎湿热瘀阻证临床症状的研究
- Author:
Juan JIAO
;
Quan JIANG
;
Wei CAO
;
Xiaopo TANG
- Publication Type:Journal Article
- Keywords:
Qingre-Huoxue Recipe;
Dampness-heat and blood-stasis syndrome;
Rheumatoid arthritis
- From:
International Journal of Traditional Chinese Medicine
2011;33(10):872-875
- CountryChina
- Language:Chinese
-
Abstract:
Objective To Evaluate the efficacy and safety of Qingre-Huoxue Recipe ( QHR ),Qingre -Huoxue Recipe and Methotrexate(QHR+MTX) in improving clinical symptoms of dampness-heat and blood-stasis syndrome of rheumatoid arthritis.Methods According to multi-center,randomized,and control intervention design,142 RA patients were randomly divided into QHR group (71 cases) and QHR+MTX group (71 cases).With clinical symptoms as evaluation indexes,FAS set and PP set were adapted for analysis.Results FAS set analysis:Both groups can significantly reduce pain VAS score [ (4.82 ± 1.98) vs (4.31 ± 1.85) ],reduce tenderness and swollen joint number[(4.87±4.05)vs(4.20±3.36)、(8.72±6.24)vs(7.14±5.03)respectively],shorten morning stiffness [ (39.56 ± 46.68) min vs (36.65 + 42.58) min] and significantly reduce the symptoms of fatigue[ (4.13 ±2.34) vs (3.74 ±2.20) ],also with good security.But there was no statistically significant difference between the two groups.Conclusion Qingre-Huoxue Recipe with MTX had no significant advantage in improving clinical symptoms in patients with the dampness-heat and blood-stasis syndrom of RA than without MTX.
