Efficacy of liver transplantation for the treatment of polycystic liver disease: a single center analysis
10.3760/cma.j.issn.1673-9752.2011.05.017
- VernacularTitle:单中心肝移植治疗多囊肝病的疗效分析
- Author:
Binsheng FU
;
Tong ZHANG
;
Hua LI
;
Genshu WANG
;
Shuhong YI
;
Chi XU
;
Yang YANG
;
Guihua CHEN
- Publication Type:Journal Article
- Keywords:
Polycystic liver disease;
Liver transplantation;
Prognosis
- From:
Chinese Journal of Digestive Surgery
2011;10(5):371-373
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of liver transplantation for the treatment of polycystic liver disease.Methods The clinical data of 8 patients with polycystic liver disease who received liver transplantation at the Third Affiliated Hospital from September 2003 to July 2009 were retrospectively analyzed.All patients underwent modified piggyback liver transplantation with vena cava plasty,and 1 of the patients received simultaneons liver-kidney transplantation.Data including acute rejections,complications,graft functions and survival time of patients were recorded.Results Operation was successfully performed on all patients.The mean operation time,anhepatic phase and operative blood loss were (7.5 +2.8)hours (range,4-11 hours),(42 + 14)minutes (range,25-70 minutes) and (2250 ± 1850)ml (range,2000-6500 ml),respectively.One patient received liver retransplantation at 45 days after primary liver transplantation because of hepatic artery stenosis.Two patients died during perioperative period.One patient died of pulmonary infection and multiple organ disfunction syndrome (MODS) at 39 days after operation,and the other one died of MODS at 59 days after operation.The median follow-up time was 60 months (range,37-93 months).Six patients survived for more than 3 years,4 patients survived for more than 5 years and 2 patients survived for more than 7 years.No acute rejection of gratis was observed at the end of the follow up.Conclusion Liver transplantation is safe and effective for the treatment of polycystic liver disease.
