Prognostic factors of primary duodenal papilla carcinoma
10.3760/cma.j.issn.1673-9752.2011.05.014
- VernacularTitle:原发性十二指肠乳头癌的预后因素分析
- Author:
Jifeng FENG
;
Wenyou CHEN
;
Dafeng CHEN
;
Song ZHOU
;
Jing LIU
- Publication Type:Journal Article
- Keywords:
Duodenal papilla carcinoma;
Prognostic factor;
Analysis
- From:
Chinese Journal of Digestive Surgery
2011;10(5):359-361
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prognostic factors of primary duodenal papilla carcinoma.Methods The clinical data of 73 patients with primary duodenal papilla carcinoma who were admitted to the Dongnan Hospital of Xiamen University from June 1995 to June 2005 were retrospectively analyzed.Ten factors including gender,age,jaundice,tumor size,course of disease,total bilirubin,tumor differentiation,lymphatic metastasis,type of surgery and degree of resection were analyzed by Log-rank test.Prognostic factors with significant difference were further analyzed by the Cox regression model.The survival curve was drawn by using the Kaplan-Meier method.Results The median survival time of the patients was 34 months.Age,jaundice,tumor size,course of disease,total bilirubin,tumor differentiation,lymphatic metastasis,type of surgery and degree of resection were correlated with the prognosis (x2 =18.315,4.562,7.989,10.660,11.138,7.995,5.423,114.464,83.383,P＜0.05),while no significant difference was found between gender and prognosis ( x2 =1.720,P ＞ 0.05 ).Multivariate analysis demonstrated that tumor differentiation,type of surgery and degree of resection were the factors influencing the prognosis of patients with duodenal papilla carcinoma (RR =2.039,2.178,5.798,P＜0.05).Conclusions Tumor differentiation,type of surgery and degree of resection are the dependent factors influencing the prognosis of patients with duodenal papilla carcinoma.The standard type of surgery and degree of resection are important for the prognosis of patients.
