MicroRNA and human cancer
10.3760/cma.j.issn.1673-422X.2011.09.003
- VernacularTitle:微小RNA与人类肿瘤
- Author:
Changzhen REN
;
Huan CHEN
;
Binghua JIAO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
MicroRNAs;
Gene expression regulation
- From:
Journal of International Oncology
2011;38(9):649-652
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA (miRNA) is a family of endogenous,non-coding small RNAs molecules that function as gene regulators.It has been revealed that miRNAs may play a critical role in many biological processes including cell proliferation,differentiation and apoptosis.Recent studies demonstrate that aberrant expression of miRNAs can lead to several human diseases even cancer.These tiny but potent molecules have the function as anti-oncogene or oncogene.Accordingly,further study of miRNAs has opened a novel avenue in the diagnosis and treatment of human cancer.
