Targeting oncolytic adenovirus therapy in pancreatic cancer
10.3760/cma.j.issn.1673-422X.2011.09.015
- VernacularTitle:靶向性溶瘤腺病毒治疗胰腺癌
- Author:
Wei WANG
;
Xiaohua TAN
- Publication Type:Journal Article
- Keywords:
Oncolytic viruses;
Gene targeting;
Pancreatic neoplasms
- From:
Journal of International Oncology
2011;38(9):690-692
- CountryChina
- Language:Chinese
-
Abstract:
Carrying out targeting an oncolytic adenovirus strategy in gene therapy of pancreatic cancer is a new direction.Currently,related research including vitro test and animal models vivo test,targeted strategies on molecular biology and gene level are carried out.Some of oncolytic adenovirus drugs have entered phase Ⅲ clinical trials.Oncolytic adenoviruses alone or in combination with other treatments,can enhanced anti-tumor effect.