Research progress of immunological rejection in xenotransplantation
10.3760/cma.j.issn.1673-4203.2011.10.020
- VernacularTitle:异种移植免疫排斥的研究进展
- Author:
Junjie LI
;
Xiao LI
;
Kefeng DOU
- Publication Type:Journal Article
- Keywords:
Xenotransplantaion,pig;
Genetical modification;
Immunological rejection
- From:
International Journal of Surgery
2011;38(10):710-714
- CountryChina
- Language:Chinese
-
Abstract:
Xenotransplantation can probably overcome the critical shortage of human organ donors for clinical transplantation.Recently,research progresses in the biology of xenograft rejection and zoonotic infections,and the generation of α1,3-galactosyltransferase-deficient pigs have moved this approach closer to clinical application,but immunological rejection is also the primary barrier in the study of xenotransplantation.This review sumarries the research progress of immunological rejection of xenotransplantation,providing some advices for the future of clinical xenotransplantation.
