Metastasis-associated gene in colon cancer 1 and tumor metastasis
10.3760/cma.j.issn.1673-422X.2011.10.009
- VernacularTitle:结肠癌转移相关基因1与肿瘤转移
- Author:
Min ZHANG
;
Delian REN
- Publication Type:Journal Article
- Keywords:
Neoplasm metastasis;
MACC1
- From:
Journal of International Oncology
2011;38(10):747-749
- CountryChina
- Language:Chinese
-
Abstract:
Recent findings indicate that metastasis-associated gene in colon cancer 1 ( MACC1 ) has an abnormal high expression in most malignant tumors.As a key regulator of HGF-MET signal pathway,MACC1 could obviously up-regulate the expression of MET and promote cancer cell's movement,invasion and metastasis.Further studies will shed light on elucidating the mechanisms of metastasis and may provide a new method for targeted therapy.
