Cytokines in the pathogenesis of mycoplasma pneumoniae pneumonia in children
10.3760/cma.j.issn.1673-4912.2011.05.030
- VernacularTitle:细胞因子在小儿肺炎支原体肺炎发病机制中的研究进展
- Author:
Tianji GAO
- Publication Type:Journal Article
- Keywords:
Mycoplasma pneumoniae pneumonia;
Pathogenesis;
Cytokines;
Children
- From:
Chinese Pediatric Emergency Medicine
2011;18(5):455-457
- CountryChina
- Language:Chinese
-
Abstract:
Cytokines and cellular immunity play a major role in the pathogenesis of mycoplasma pneumoniae pneumonia(MPP).Studies have shown that mycoplasma pneumoniae infection,the concentrations of interleukin(IL)-4,interferon-γ,IL-6 and IL-13 increased,but the concentration of IL-10 decreased.The concentrations of IL-2,IL-8 and tumor necrosis factor-α have various results which still need further discussion.Through clinical monitoring of a variety of cytokines by the changes of concentrations,it can confirm the diagnosis of MPP,determine the severity of infection,provide the basis for prognosis and provide the theoretical basis for immunotherapy of MPP.
