Efficacy of pancreaticoduodenectomy combined with vascular resection and reconstruction
10.3760/cma.j.issn.1673-9752.2011.05.009
- VernacularTitle:联合血管切除重建的胰十二指肠切除术疗效分析
- Author:
Jiaqian SUN
;
Chaobin ZHANG
;
Leida ZHANG
;
Geng CHEN
;
Ping BIE
;
Huaizhi WANG
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Pancreaticoduodenectomy;
Vascular reconstruction;
Complication;
Survival rate
- From:
Chinese Journal of Digestive Surgery
2011;10(5):344-346
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of pancreaticoduodenectomy (PD) combined with vascular resection and reconstruction.Methods The clinical data of 56 patients who received PD combined with vascular resection and reconstruction at the Southwest Hospital of Third Military Medical University from January 2007 to May 2011 were retrospectively analyzed.The incidence of perioperative complications,mortality and postoperative conditions were also analyzed.Results The mean operation time and intraoperative blood transfusion were 473 minutes (range,234-853 minutes) and 781 ml (range,0-900 ml),respectively.Seven patients did not receive blood transfusion.The median period of hospital stay was 25.9 days (range,17-100 days).A total of 43 patients underwent PD combined with vascular reconstruction.The incidence of perioperative complications and mortality rate were 34％ (19/56) and 7％ (4/56),respectively.There were 42 patients with pancreatic ductal adenocarcinoma,5 with ampullary carcinoma,3 with distal bile duct carcinoma,4 with papillary carcinoma of duodenum,1 with pancreatic neuroendocrine carcinoma and 1 with pancreatic serous cystadenoma.All patients were followed up till August 2011,and the 1-year survival rate was 57％ (32/56).The mean survival time was 13.5 months.The weight of 32 surviving patients increased and no abdominal pain occurred.Within 3 months after the operation,5 patients had slight diarrhea and were administered antidiarrheal; thrombosis in the artificial blood vessels and peritoneal effusion were found in 1 patient,while 6 months later,collateral circulation was formed and the peritoneal effusion was diminished.Conclusion PD combined with vascular resection and reconstruction can improve the quality of life for patients with pancreatic cancer and with blood vessels involvement.
