The detection and significance of cardiac troponin Ⅰ, myoglobin and creatine kinase MB in old patients with acute myocardial infarction
10.3760/cma.j.issn.1673-4904.2011.24.003
- VernacularTitle:心肌肌钙蛋白Ⅰ、肌红蛋白和肌酸激酶同工酶在老年急性心肌梗死中的检测及意义
- Author:
Aifeng LI
;
Weihong LI
;
Haining LIU
;
Xiqiang LW
;
Aiguo YAN
- Publication Type:Journal Article
- Keywords:
Tropanin Ⅰ;
Myoglobin;
Creatine kinase,MB form;
Myocardial infarction
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(24):7-9
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the changes and significances of cardiac troponin Ⅰ (cTnⅠ),myoglobin (Mb) and creatine kinase MB (CK-MB) in old patients with acute myocardial infarction(AMI).MethodThe levels of cTnⅠ, Mb and CK-MB in 89 cases with AMI patients (AMI group) and 100 healthy controls (control group) were detected and compared. ResultsThe levels of cTnⅠ, Mb and CK-MB in AMI group were ( 8.15 + 3.26) μ g/L, (478.45 ± 96.87 ) μ g/L and ( 128.17 ± 53.26 ) U/L, while were (0.03 ±0.02) μ g/L, (21.61 + 9.38 ) μ g/L and (9.53 ± 2.94) U/L in control group, the levels of cTnⅠ, Mb and CK-MB in AMI group were significantly higher than those in control group(P ＜ 0.05 ). The sensitivity rate of cTnⅠ,Mb and CK-MB for detecting AMI was 95.5％ (85/89), 97.8％ (87/89) and 87.6％ (78/89), and the specificity rate was 98.0％(98/100), 82.0％(82/100) and 94.0％(94/100). ConclusionThe levels of cTnⅠ, Mb and CK-MB are significantly increased in AMI patients, which cTnⅠ for detecting AMI has high sensitivity and specificity.
