Case-control study on ginkgo-dipyridimolum and mecobalamin for treatment diabetic peripheral neuropathy
10.3760/cma.j.issn.1008-6706.2011.20.014
- VernacularTitle:银杏达莫联合甲钴胺治疗糖尿病周围神经病变
- Author:
Jinfeng CHEN
;
Xueqin WANG
;
Jianbin SU
;
Feng XU
- Publication Type:Journal Article
- Keywords:
Diabetes;
Diabetic peripheral neuropathy;
Ginkgo-dipyridimolum;
Meeobalamin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(20):2764-2765
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effect of the combined therapy of ginkgo-dipyridimolum and mecobalamin for diabetic peripheral neuropathy (DPN).MethodsA total of 102 DPN cases were randomly divided into treatment group(n =50) and control group(n =52).The treatment group was given ginkgo-dipyridimolum and mecobalamin, and the control group was given only mecobalamin for 4 weeks.We observed the change of symptom and sign of both groups before and after treatment,and the MNCV and SNCV of median nerve,ulnar nerve and peroneal nerve were detected.ResultsIn the treatment group, the improvement of DPN symptoms (x2 = 10.090, P ＜ 0.01) and nervous conducting speed were much more obvious than that in the control group(MNCV of median nerve, ulnar nerve and peroneal nerve was(49.12 ± 3.32) m/s, (52.11 ± 3.12) m/s and(47.32 ± 3.21) m/s respectively; SNCV of median nerve,ulnar nerve and peroneal nerve was(47.13 ± 2.56) m/s, (55.12 ± 2.31) m/s, (46.78 ± 2.66) m/s respectively,all P ＜0.05).ConclusionThe combined therapy of ginkgo-dipyridimolum and mecobalamin could effectively improve the therapeutic outcome of DPN, and the treatment was safe and worthy of widespread use.
