Association between bacterial vaginosis and high risk human papilloma virus in female genital tract

VernacularTitle:细菌性阴道病与高危型人乳头瘤病毒感染的关系
Author: Ranli KE ; Yingying HUA
Publication Type:Journal Article
Keywords: Bacterial vaginosis; Human papillomavirus; Cervical intraspithelial neoplasia
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(18):2475-2476
CountryChina
Language:Chinese
Abstract: ObjectiveTo study whether the presence of bacterial vaginosis (BV) increased the infection rate of high risk human papilloma virus(HR-HPV) in female genital tract. MethodsThe BV group had 867 patients who were diagnosed as bacterial vaginosis,and the control group had 610 female healthy volunteers without BV. Both the BV patients and the healthy volunteers were tested for HR-HPV infection rate and clearance rate. ResultsThe HR-HPV infection rate of BV group was 17.2％ ,higher than the control group's 10.7％ (P ＝ 0.000) ,and 1 year HR-HPV clearance rate of BV group was 77. 6％, a little lower than the control group' s 84. 8％ ( P ＝ 0. 414).ConclusionThere was significant correlation between the presence of BV and HR-HPV infection. But 1 year HPV clearance rate had no difference between BV group and control group, indicated that efficient treatment to BV enhanced the vagina's anti-infection ability and decreased the incidence of HPV infection so as to reduce the incidence of CIN and cervical cancer.