Control study of buprenorphine sublingual tablets and methadone for heroin addicts on out patients treatment during recovery period

VernacularTitle:丁丙诺啡舌下含片与美沙酮用于海洛因依赖门诊稽延期治疗的对照研究
Author: Guangsheng NIU ; Wanjun DU ; Yuming WANG ; Jie ZHENG
Publication Type:Journal Article
Keywords: Buprenorphine sublingual tablets; Methadone; Heroin addicts
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(16):2193-2195
CountryChina
Language:Chinese
Abstract: ObjectiveTo observe the effect of buprenorphine sublingual tablets (Bup) and methadone for heroin addicts on out patients treatment during recovery period. MethodsHeroin addicts who completed acute drug detoxification treatment were assigned in the order of cross to the observation group and control group. The observation group and the control group were treated with Bup and methadone, respectively for six months. Both groups were observed on the time of keeping heroin abstinence during the treatment and were assessed with Anxiety Scale before and after Bup or methadone treatment. ResultsBup group kept abstinence from heroin longer than methadone group ( P ＜0.01 ) ,and had lower anxiety scores( P ＜0.05). ConclusionBupernorphine sublingual tablets used for out patients at recovery period could better alleviate heroin addicts' anxiety and prolong their abstinence time.