A comparative study of intravenous thrombolysis and late intracoronary stenting in treatment of acute ischemic stroke onset using 99mTc2ECD SPECT imaging

VernacularTitle:溶栓及延迟支架置入治疗急性脑梗死脑灌注显像的研究
Author: Xiaofen XIE ; Yangjie YU ; Zhe GUO
Publication Type:Journal Article
Keywords: Radio nuclide imaging; Brain infarction; Stenting
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(17):2329-2330
CountryChina
Language:Chinese
Abstract: Objective To evaluate and compare the therapeutic effect among intravenous rt2PA thrombolysis,thrombolysis plus delayed intracoronary stenting for acute ischemic stroke onset using 99mTc2ECD SPECT imaging.Methods 45 cases of acute ischemic stroke onset were divided into two groups which were the thrombolysis group( n = 23 ) ,thrombolysis plus delayed stenting group (n = 22), 99mTc2MIBI SPECT imaging was performed 3 weeks after thrombolysis therapy or 1 week after intracoronary stenting. The score of 99mTc2MIBI brain uptake were analyzed semiquantitatively and the total score of myocardial 99mTc2ECD uptake was calculated. Results The scores of the 2 groups were( 12. 4 ± 4. 6) and( 9. 7 ± 3. 8 ) respectively, Significant difference was shown in the thrombolysis plus delayed stenting group compared with the thrombolysis group (P ＜ 0. 01 ). Conclusion 99mTc2ECD SPECT imaging had been proved to be an objective parameter for evaluating the therapeutic effect of the various treatments of AMI. Thrombolysis plus delayed stenting was more effective than thrombolysis.