The clinical value of Aescuven forte in the treatment of the mild to moderate craniocerebral trauma in the young patients
10.3760/cma.j.issn.1008-6315.2011.09.028
- VernacularTitle:迈之灵对青年患者轻中度颅脑损伤的保护作用
- Author:
Libo LIU
;
Zhongzhi TANG
;
Qing CHENG
;
Jing HUANG
- Publication Type:Journal Article
- Keywords:
Aescuven forte;
Craniocerebral trauma;
Clinical assessment;
Random control;
Young people
- From:
Clinical Medicine of China
2011;27(9):970-972
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo assess the clinical efficacy and safety of Aescuven forte in the young patients with craniocerebral trauma.Methods Eighty patients diagnosed with craniocerebral trauma were randomized into treatment group and control group,in which the patients were given Aescuven forte tablets 0.3 g t.i.d for 30 days and routine treatmentsrespectively.Barthel index, Mini-Mental State Examination (MMSE)scale, Glasgow Coma Scale(GCS) and other clinical parameters were used to evaluate the efficacy by comparing their values before and 30 days after treatment.Results In the Aescuven forte treatment group, 35.0％ (14/40) and 50.0％ (20/40) of the patients showed complete response and partial response with the total response rate of 85.0％ (34/40) ,while they were 20.0％ (8/40) ,52.5％ (21/40) and 72.5％ (29/40) in the control group,respectively(x2 = 18.78 ,P ＜ 0.05) .The incidence of complications in Aescuven forte-treated group was lower than that in the control group.No severe adverse events occurred.Conclusion Aescuven forte is a safe and effective vasoactive drug for the recovery of craniocerebral trauma-caused neurological disorders and mental deterioration in young patients.
