Effect of the levonorgestrel-releasing intrauterine device (Mirena) in the treatment of dysfunctional uterine bleeding

VernacularTitle:左炔诺孕酮宫内缓释系统对功能失调性子宫出血治疗效果观察
Author: Yinghui ZHOU ; Yuanyuan WU
Publication Type:Journal Article
Keywords: Levonorgestrel-releasing intrauterine device; Dysfunctional uterine bleeding; Endometrial hyperplasia
From: Clinical Medicine of China 2011;27(9):993-995
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy and side-effects of the levonorgestrel-releasing intrauterine device (Mirena) in the treatment of dysfunctional uterine bleeding .Methods 45 cases of dysfunctional uterine bleeding diagnosed by pathology were installed with Mirena.The endometrial thickness by ultrasound hemoglobulin increase and pathologic changes of endometria were recorded before and 24 months after the installation.ResultsThe endometrial thickness before and after the insertion of Mirena were(15.6 ±4.2) mm and (3.2 ± 1.3)mmrespectively (P ＜ 0.01) .Six months after the insertion of Mirena, patients' hemoglobulin was significantly increased from (97.6 ± 8.2)g/L to (123.7 ± 8.1)g/L (U = 2.26, P ＜ 0.05) .After the installation of Mirena, patient experienced metrorrhagia.Conclusions Mirena is a device providing effective and continual therapy for dysfunctional uterine bleeding .It can not only significantly reduce the menstrual blood loss but also reverse the complex hyperplasia effectively.