Epidemiological characteristics of patients acquiring human immunodeflciency virus infection through sexual contact or blood transfusion
10.3760/cma.j.issn.1000-6680.2011.09.007
- VernacularTitle:经性传播与供/受血传播人类免疫缺陷病毒感染者特点分析
- Author:
Rongrong YANG
;
Xien GUI
;
Yongxi ZHANG
;
Yong XIONG
;
Yuping RONG
;
Yajun YAN
- Publication Type:Journal Article
- Keywords:
Acquired immunodeficiency syndrome;
HIV infections;
Sexually transmitted diseases,viral;
Blood transfusion;
Papillomaviridae
- From:
Chinese Journal of Infectious Diseases
2011;29(9):540-543
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the epidemiological characteristics of patients acquiring human immunodeficiency virus (HIV) infection through sexual contact or blood transfusion. Methods A total of 679 HIV/AIDS patients were recruited. The informed consents were obtained from all participants. CD4+T lymphocyte count, anti-syphilis and HIV-1 subtype of recruited cases were tested, and anti-HIV of their spouses was tested.Human papillomavirus (HPV) genotyping was performed in female patients. The data were analyzed by t test and chi square test. ResultsThere were 348 cases in heterosexual transmission group (STG) and 331 in blood transfusion group (BTG). HIV-1 genotyping was performed in 120 STG cases and 90％ (108/120) were mixed genotypes; HIV1 genotypes in 107 BTG cases were all subtype B'. Curable sexual transmitted diseases (STDs) in STG and BTG were identified in 293 and 156 cases, respectively. The incidence of cSTDs were 34.1％ (100/293) in STG and 5.8％ (9/156) in BTG (x2 =44. 541, P＜0.01). Forty-three females in STG and 138 females in BTG were tested for HPV, and the HPV infection rates ware 67.4％ (29/43) and 26.8％ (37/138), respectively (x2 =23. 361, P＜0.01). Among 348 cases in STG and 331 cases in BTG, the rate of HIV transmission between couples was 48.9％ (170/348) and 23.3％ (77/331),respectively (x2 =47. 991, P＜0. 05). ConclusionsThe diagnosis of HIV infection acquired through sexual contact is usually late, which results in a relatively high risk for viral transmission. Furthermore, the co-infection of HIV and HPV or other sex transmission disease is common.
