Evaluation of ultrasound elastography in the diagnosis of prostate cancer

VernacularTitle:经直肠超声弹性成像在前列腺癌诊断中的应用
Author: Xu ZHANG ; Pintong HUANG ; Chunmei LIU ; Zhimin YE ; Xueming LIU ; Guoqiang MO ; Jiang ZHU
Publication Type:Journal Article
Keywords: Endosonography; Prostatic neoplasms; Elastography; Strain ratio
From: Chinese Journal of Ultrasonography 2011;20(9):775-778
CountryChina
Language:Chinese
Abstract: Objective To evaluate the application of transrectal ultrasound elastography (TRE) in the detection of prostate cancer(PCa).Methods One hundred and eighteen patients with suspected PCa were enrolled in this study.Each patient underwent transrectal ultrasound (TRUS), TRE and sonography guided prostatic biopsy on the same day.The accuracy rate of PCa detection using TRE were compared with the pathology results.Results Patients with PCa were detected in 62 of the 118 patients,including 48 cases by TRE and 38 cases by TRUS.The sensitivity for TRE (73.6％) was significantly higher than that of TRUS (52.8％) in periurethral zone(P ＜0.05).The sensitivity and specificity for strain ratio(SR) in predicting PCa were 85.7％ and 67.7％ respectively(cut off value：3.6,area under the curve 0.8, P ＜0.01,95％CI [0.68 - 0.92]).Conclusions TRE can detect PCa in the periurethral zone with good accuracy and has potential to increase ultrasound-based PCa detection rate.