Glycolysis and tumor
10.3760/cma.j.issn.1673-422X.2011.08.009
- VernacularTitle:糖酵解与肿瘤
- Author:
Xiaowei XU
;
Xiangjun MENG
;
Chun WANG
- Publication Type:Journal Article
- Keywords:
Glycolysis;
Neoplasms;
Hypoxia-inducible factor 1
- From:
Journal of International Oncology
2011;38(8):585-589
- CountryChina
- Language:Chinese
-
Abstract:
Tumor cells obtain energy mainly by glycolysis to maintain growth and proliferation. It is related to the DNA mutations of mitochondria and anti-oncogene mutations. Inhibition of glycolysis can inhibit proliferation and kill tumor cells. The rate-limiting enzyme of glycolysis and hypoxia inducible factor may be the new targets for cancer therapy.
