Aberrant gap junction and tumor
10.3760/cma.j.issn.1673-422X.2011.08.008
- VernacularTitle:细胞间隙连接异常与肿瘤
- Author:
Wang JUAN
;
Xia JUAN
- Publication Type:Journal Article
- Keywords:
Connexins;
Gap junction;
Neoplasms;
Cell communication
- From:
Journal of International Oncology
2011;38(8):582-585
- CountryChina
- Language:Chinese
-
Abstract:
Gap junctions are membrane structures made of intercellular channels that allow directly exchange of material and information between adjacent cells. It is the structural basis of gap junctional intercellular communication. Gap junction is aberrant frequently in variety of cancers, which relatives with tumor genesis and metastasis. New anti-cancer drugs targeting gap junctions will be a new direction for tumor treatment.
