Prevalence of metabolic syndrome in patients with primary aldosteronism
10.3760/cma.j.issn.1000-6699.2011.09.005
- VernacularTitle:原发性醛固酮增多症患者中代谢综合征的患病情况
- Author:
Xuan MA
;
Hongmei WANG
;
Juan LI
;
Xinguo WANG
;
Lili ZHANG
;
Dengpan LIANG
;
Menghui WANG
;
Nanfang LI
- Publication Type:Journal Article
- Keywords:
Primary aldosteronism;
Metabolic syndrome;
Hypertension;
Aldosterone
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(9):724-728
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the prevalence of metabolic syndrome (MS) in patients with primary aldosteronism(PA) and the correlation with plasma aldosterone concentration. MethodsThe incidence of MS was retrospectively analyzed in 216 patients with PA from October 2008 to July 2010. Results( 1 ) The prevalence of MS was 47. 69％ in the patients with PA. As the individual components of MS, the incidence of overweight/obesity,raised blood triglyceride ( TG ) level, impaired glucose regulation ( IGR), lowered high-density lipoprotein-cholesterol ( HDL-C), and diabetes mellitus( DM ) was 51.13％, 22. 52％, 19.62％, 3.82％, and 2.94％, respectively. (2)The most common combination of MS components was overweight/obesity+high TG, followed by overweight/obesity+ lowered HDL-C, and overweight/obesity + DM, with the incidence of 35. 19％,15.74％, and 11.57％,respectively. (3) The incidence of overweight/obesity and IGR was raised progressively with the increasing plasma aldosterone level. (4) The prevalence of MS was significantly lower in Han patients (45.3％) than in Uygur ( 64. 0％ ), but higher than in Kazakh (42. 9％, both P＜0. 05 ). ConclusionsThe prevalence of MS in patients with PA was high. The prevalences of MS and its components were gradually rising with plasma aldosterone level.
