Effects on QT dispersion in patients who received maintenance hemodialysts by dialysate with different concentration of potassium
10.3760/cma.j.issn.1008-6706.2011.19.009
- VernacularTitle:不同钾浓度透析液对维持性血液透析患者QT离散度的影响
- Author:
Wenhui SONG
- Publication Type:Journal Article
- Keywords:
Renal dialysis;
Potassium;
QT dispersion;
Arrhythmia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(19):2609-2610
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effects on QT dispersion in patients who received maintenance hemodialysis by dialysate with different concentration of potassium. MethodsTook 57 patients who received maintenance hemodialysis as dialysis group, took another 30 healthy subjects as control group, patients in dialysis group alternatively received hemodialysis by dialysate with potassium concentration of 2.0mmol/L and 3.0mmol/L once. QT interval of both groups were recorded by 12-lead synchronized ECG and then QT dispersion and QTcd were calculated. ResultsQTd and QTcd of dialysis group were(52.7 ±8.2) and(63.2 ±9.0)ms respectively and which were significantly higher than control group, the difference between groups was statistically significant( t =2. 638,2. 750, both P ＜ 0.05 ) ; QTd, QTcd and the incidence of arrhythmia of 2.0mmol/L K + group were ( 63.5 ± 7.6), ( 72.3 ± 8.0)ms and 22.8％ ( 13/57)respectively and which were all significantly higher than 3.0mmol/L K + group,the differences between groups were statistically significant ( t =2. 245,2.351, x2 =5. 599, all P ＜ 0.05 ). ConclusionQT dispersion reflectsed the heterogeneity of ventricular repolarization and electrical instability,and the use of dialysate with potassium concentration of 3.0mmol/L could shorten QT interval and reduce the incidence of arthythmia.
