Follicle stimulating hormone and tumor angiogenesis
10.3760/cma.j.issn.1673-422X.2011.08.004
- VernacularTitle:卵泡刺激素与肿瘤血管生成
- Author:
Tao LIU
;
Jinghua REN
;
Gang WU
- Publication Type:Journal Article
- Keywords:
Follicle stimulating hormone;
Angiogenesis inducing agents;
Drug resistance,neoplasm
- From:
Journal of International Oncology
2011;38(8):572-574
- CountryChina
- Language:Chinese
-
Abstract:
Recent researches show that follicle stimulating hormone (FSH) plays an important regulatory role in the angiogenesis of ovarian cancer by influencing the level of some factors such as hypoxia inducefactor-1 ( HIF-1 ) ,vascular endothelial growth factor (VEGF). Meanwhile, recent studies report that FSH and FSH receptor(FSHR) may also participate in the angiogenesis of other solid tumors like lung cancer. FSH is closely related to the tumor angiogenesis, which provides a novel therapeutic target for anti-angiogenesis thera-py.
