Value of contrast-enhanced ultrasound in ultrasound-guided percutaneous biopsy of peripheral lung lesions
10.3760/cma.j.issn.1004-4477.2011.08.008
- VernacularTitle:超声造影对超声引导下经皮肺穿刺活检的价值
- Author:
Bingsheng CAO
;
Xiaolin LI
;
Juan DENG
;
Guoqing LIAO
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Lung neoplasms;
Biopsy,needle
- From:
Chinese Journal of Ultrasonography
2011;20(8):669-671
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of contrast-enhanced ultrasound (CEUS) on the diagnostic efficacy of ultrasound-guided percutaneous biopsy of peripheral lung lesions. Methods Ninty-six patients with pleural-based lesions underwent percutaneous ultrasound-guided biopsy. Of the 96 patients,54patients underwent CEUS before biopsy and enhancement information was referred for the selecting of tissue sampling site. The rest of 42 patients didn' t undergo CEUS before biopsy. The difference in the diagnostic accuracy between the two groups was analyzed to evaluate the value of CEUS before biopsy.Results Of the 52 patients in the CEUS group,48 were malignant,and 6 were benign. Of the 42 patients in the un-CEUS group,36 were malignant, and 6 were benign. Necrosis (areas lacking of enhancement) was demonstrated in 41.7％ (20/48) of the patients with malignant lesions in CEUS group, and necrosis incidence was increased with the increase of the dimension of the malignant lesions. No necrosis area was demonstrated in 6 benign lesions. The rate of successful initial biopsy in CEUS group (98.1 ％ ,53/54) was statistically higher than that in un-CEUS group ( 85.7％, 36/42 ) ( P ＜ 0.05 ). Tissue necrosis and denaturalization attributed to most of the inconclusive pathologic diagnosis. Conclusions CEUS before transthoracic peripheral lung lesion biopsy improved the diagnostic accuracy of the procedure by providing information for differentiating viable or necrotic tissue and consequently provide more accurate information about the site of biopsy.
