Research advances in cord blood cytokine induced killer cells
10.3760/cma.j.issn.1673-4408.2011.05.024
- VernacularTitle:脐血CIK细胞的研究进展
- Author:
Xiao QIONG
- Publication Type:Journal Article
- Keywords:
Cord blood;
Cytokine induced killer cells;
Immunotherapy
- From:
International Journal of Pediatrics
2011;38(5):500-502
- CountryChina
- Language:Chinese
-
Abstract:
Cytokine induced killer (CIK)cells are immune effector cells generated from mononuclear cells induced by many cytokines.CIK cells have several advantages, such as rapid proliferation, broad spectrum killing activity, high tumoricidal activity and non-major histocompatibility complex restriction.Recently, cord blood derived CIK cells have attracted extensive concerns because of its faster proliferation, higher tumoricidal activity and lower incidence of GVHD compared with adult peripheral blood derived CIK cells. This paper will review the biological characteristics, clinical application and research advances of cord blood derived CIK cells.
