A systematic review of racial differences in cerebral vasospasm after aneurysmal subarachnoid hemorrhage: comparsion of patients in China and in Europe
10.3760/cma.j.issn.1673-4165.2011.07.007
- VernacularTitle:动脉瘤性蛛网膜下腔出血后脑血管痉挛的种族差异的系统评价:中国患者与欧洲患者的比较
- Author:
Chunhui WU
;
Guozhong SIMA
;
Xiaojun ZHANG
;
Chaojun YAN
;
Yongzhong FAN
- Publication Type:Journal Article
- Keywords:
Vasospasrm,intracranial;
Subarachnoid henorrhage;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2011;19(7):525-530
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze and compare the incidence of cerebral vasospasm (CVS) in patients with aneurismal subarachnoid hemorrhage(aSAH) in China and in Europe.Methods A literature search was performed for all the papers investigating the incidence,diagnosis, treatment or prognosis of CVS after aSAH using the MEDLINE and China Knowledge Resource Integrated Database (CNKI) from January 1, 1990 to December 31, 2010.The incidences of angiographic CVS, symptomatic CVS and CVS-related infarcts were recorded.The incidences of CVS between Chinese and white men in Europe were compared. Results A total of 237 articles were searched via CNKI and reference reviews, and 9 of the studies met the inclusion criteria. A total of 172 articles were searched via MEDLINE and reference reviews, and 18 of the studies met the inclusion criteria. The risk of occurring symptomatic CVS in patients with aSAH in Chinese was significantly higher than that in white men in Europe (relative risk,2. 063, 95% confidence interval 1.816-2. 343, P <0. 001). Conclusions The incidence of CVS in patients with aSAH in Chinese was significantly higher than that in white men in Europe,indicating the pathogenesis of CVS may have genetic basis.